Isolated echogenic intracardiac focus
Overview: An EIF is a common finding, seen in 3-5% of normal fetuses. When an EIF is identified, an experienced provider should perform a detailed fetal anatomic survey and assess for aneuploidy risk factors.
Diagnosis/definition: An EIF is a small, echogenic area within the fetal cardiac ventricle that has a sonographic brightness equivalent to bone. An EIF is not a structural or functional cardiac abnormality.
Epidemiology/Incidence: EIFs are seen in 3-5% of normal fetus, with prevalence as high as 30% in fetuses of Asian mothers.
- Evaluation includes a detailed anatomic survey by an experienced provider and assessment of risk factors for aneuploidy, including maternal age, results of other screening or diagnostic tests, and family history.
- If an isolated EIF is identified, multiply the patient’s a priori risk by a published likelihood ratio such as 2.9 to generate a modified risk.
- No specific follow-up of EIF is recommended.