Data Sets for MFMs
Maintained by the SMFM Research Committee, the data sets below can be used to support SMFM members' research. If you have questions or need assistance, contact Kerri Wade.
Wide-Ranging Online Data for Epidemiologic Research (WONDER)
Centers for Disease Control and Prevention
Study Description: Online collection of nearly 20 publicly available datasets including U.S. births, deaths, vaccinations, environmental exposures and population estimates. It contains the only publicly-available data set for maternal mortality data.
Availability: Free, no formal application required.
Infant Feeding Practices Study II (IFPS II) and Year Six Follow-Up (Y6FU)
Centers for Disease Control and Prevention
Study Description: Longitudinal study from 2005-2007 that followed about 2,000 mother-infant pairs from the third trimester of pregnancy throughout the first year of life to study a variety of infant feeding practices. In 2012, the FDA and CDC conducted the Year Six Follow-Up (Y6FU) study to characterize the health, development and dietary patterns of these children at 6 years of age.
Availability: Free, requires email request.
National Immunization Survey Study
Centers for Disease Control and Prevention
Study Description: Group of telephone surveys conducted by CDC’s NCIRD used to obtain vaccination coverage rates for U.S. children 19-35 months (NIS-Child) and for U.S. adolescents 13-17 years (NIS-Teen).
Availability: Free, no formal application required.
Pregnancy Risk Assessment Monitoring System (PRAMS)
Centers for Disease Control and Prevention
Study Description: Surveillance project that collects state-specific, population-based data on maternal attitudes and experiences before, during, and shortly after pregnancy.
Availability: Free, requires formal application and signed data sharing agreement.
Sudden Unexpected Infant Death (SUID) Case Registry
Centers for Disease Control and Prevention
Study Description: Case Registry in participating U.S. states aimed to provide population-based SUID surveillance and to categorize SUID cases using standard definitions.
Availability: Requires formal email to representatives at the NIH.
National Health and Nutrition Examination Survey (NHANES)
CDC National Center for Health Statistics
Study Description: Nationwide survey designed to collect information about the health and diet of people in the United States.
Availability: Free, no formal application required.
National Health Interview Study (NHIS)
CDC National Center for Health Statistics
Study Description: National survey used to monitor trends in illness and disability and to track progress toward achieving national health objectives.
Availability: Free, no formal application required.
National Survey of Family Growth (NSFG)
CDC National Center for Health Statistics
Study Description: National survey that gathers information on family life, marriage and divorce, pregnancy, infertility, use of contraception, and men’s and women’s health.
Availability: Free, no formal application required.
Behavioral Risk Factor Surveillance System (BRFSS)
Centers for Disease Control and Prevention
Study Description: Health-related telephone surveys that collect state data about U.S. residents regarding their health-related risk behaviors, chronic health conditions, and use of preventive services. BRFSS completes more than 400,000 adult interviews each year, making it the largest continuously conducted health survey system in the world.
Availability: Free, no formal application required.
National Vital Statistics System (NVSS)
CDC National Center for Health Statistics
Study Description: Oldest and most successful example of intergovernmental data sharing that collects and disseminates the Nation’s official vital statistics on births, marriages, divorces, and deaths.
Availability: Free, no formal application required.
National Health Care Surveys (NHCS)
CDC National Center for Health Statistics
Study Descriptions: Collection of 14 surveys designed to answer key questions of interest to health care policy makers, public health professionals, and researchers. These include the factors that influence the use of health care resources, the quality of health care, including safety, and disparities in health care services provided to population subgroups in the U.S.
Availability: Free, no formal application required.
Early Childhood Longitudinal Study, Birth Cohort (ECLS-B)
Department of Education
Study Description: Nationally representative sample of approximately 14,000 children born in the U.S. in 2001 aimed to provide detailed information about children's early life experiences including health, development, care, and education from birth through kindergarten.
Availability: Free, formal application required.
Biospecimen Repository Access and Data Sharing (BRADS)
Eunice Kennedy Shriver National Institute of
Child Health and Human Development
Study Description: Repository of data and biospecimen collections from epidemiologic studies and clinical trials including:
Collaborative Perinatal Project (Multiple studies) – data and biospecimens
Diabetes and Early Pregnancy – data only
Vaginal Infections and Prematurity (VIP) – data and biospecimens
Neural Tube Defects (NTD) – data only
Danish Perinatal Study – data only
Norway-Alabama Fetal Growth Study – data and biospecimens
Calcium for Preeclampsia Prevention (CPEP) Trial – data and biospecimens
NIH-DC Initiative to Reduce Infant Mortality in Minority Populations (Multiple studies) – data only
Epidural Analgesia During Labor and Delivery – data only
Longitudinal Study of Vaginal Flora (LSVF) – data and biospecimens
Swimming Lessons and the Risk of Drowning in Children – data only
Management of Early Pregnancy Failure Trial – data only
Availability: Free, formal application and data use agreement required.
Global Alliance to Prevent Prematurity and Stillbirth (GAPPS) Bioservices
Study Description: Widely-accessible biobank of more than 136,000 specimens from over 2,500 diverse pregnant women and their infants linked to extensive demographic and medical data. This biobank is aimed to study predictors of preterm birth, stillbirth, adverse pregnancy outcomes and learn more about the fetal origins of adult diseases.
Availability: Free, formal application required.
Global Pregnancy Collaboration (CoLab)
Study Description: International consortium of centers that enables sharing of data and biological samples with investigators worldwide to facilitate research studies of adverse pregnancy outcomes.
Availability: Formal application and sponsorship by CoLab representative required.
National Birth Defects Prevention Study (NBDPS)
Centers for Disease Control and Prevention
Study Description: One of the largest U.S. studies that looks at risks and potential cause of birth defects among 40,000 women who delivered babies between 1997-2011.
Availability: Requires formal application and collaboration with participating center.
Data and Specimen Hub (DASH)
Eunice Kennedy Shriver National Institute of
Child Health and Human Development
Study Description: Centralized system that houses de-identified data from NICHD supported studies for use in secondary research such as:
Antenatal Late Preterm Steroids: A Randomized Placebo Controlled Trial (MFMU)
Clinical Trial of Low-Dose Aspirin (60mg) as a Preventive of Preeclampsia (MFMU)
Clinical Trial of Low-Dose Aspirin to Prevent Preeclampsia in High Risk Women
Community and Child Health Network
Early Blood Pressure Management in Extremely Preterm Infants Feasibility Pilot Study
Early-Onset Sepsis in an NICHD/CDC Surveillance Study I and II
Cluster-Randomized Trial of Ultrasound Use to Improve Pregnancy Outcomes in Low Income Country Settings
Genomic and Proteomic Network for Preterm Birth Research GWAS Case Control Study
Global Network’s Maternal Newborn Health Registry
Maternal Antiviral Prophylaxis to Prevent Perinatal Transmission of Hepatitis B Virus in Thailand
Mid-Trimester Endovaginal Sonography in Women at High Risk for Spontaneous Preterm Delivery (MFMU)
National Children’s Study
Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be
Obstetrical Determinants of Neonatal Survival (MFMU)
Preconception Maternal Nutrition Trial Women First
Screening for Risk Factors for Spontaneous Preterm Delivery (MFMU)
Child Health and Development Studies Original Cohort
Consortium on Safe Labor
Availability: Free, formal application and data use agreement required.
National Inpatient Sample
AHRQ Healthcare Cost
and Utilization Project
Study Description: Largest publicly available all-payer inpatient healthcare database designed to produce U.S. regional and national estimates of inpatient utilization, access, charges, quality and outcomes using ICD diagnosis and procedure codes along with other demographic data.
Availability: Requires purchase, no formal research proposal required.
MarketScan Research Databases
IBM
Study Description: One of the largest proprietary U.S. claims databases that includes hospital discharge database and electronic health record database as well as datasets that combine claims data with other patient and employee data.
Availability: Requires purchase, no formal research proposal required.
Page Last Updated: February 12, 2021